Application Note: WB: 1:500-1:2000. IHC-P: 1:50-1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Form: Liquid
Buffer (with preservative): PBS, pH 7.4, 150mM NaCl, 50% glycerol, 0.02% sodium azide.
Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration.)
Background: This gene encodes a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases. The encoded protein plays a role in inflammation and cell death in response to tissue damage, pathogen recognition, and as part of developmental regulation. RIPK1/RIPK3 kinase-mediated necrosis is referred to as necroptosis. Genetic disruption of this gene in mice results in death shortly after birth. [provided by RefSeq, Aug 2017]
Uniprot ID: Q13546
Antigen Species: Human
Immunogen: A synthesized peptide derived from human RIPK1 (Accession Q13546), corresponding to amino acid residues E371-T395.
Purification: Purified by antigen-affinity chromatography
Conjugation: Unconjugated
Full Name: receptor interacting serine/threonine kinase 1