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Applications: Useful for studying enzyme kinetics and screening small molecular inhibitors for drug discovery and HTS applications.
Background: RIPK2 (receptor-interacting protein kinase 2) has been shown to mediate the activation of pro-inflammatory signals by NODs (Nucleotide-binding oligomerization domain-containing proteins),suggesting RIPK2 may be a promising therapeutic target in autoimmune and inflammatory diseases.
Description: The RIPK2 Kinase Assay Kit is designed to measure RIPK2 kinase activity for screening and profiling applications using ADP-Glo® Kinase Assay as a detection reagent.
Storage Stability: Up to 6 months when stored as recommended.
Supplied As: The RIPK2 Kinase Assay Kit comes in a convenient 96-well format, with enough purified recombinant RIPK2 enzyme, RIPK substrate, ATP and kinase assay buffer for 100 enzyme reactions.
Warnings: Avoid multiple freeze/thaw cycles.
Biosafety Level: Not applicable (BSL-1)
References: Canning P., et al. Chem. & Biol. 22(9): 1174-1184 (2015)
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