Clone Name: GT1303
Application Note: WB: 1:500 - 1:2000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 217
Form: Liquid
Buffer (with preservative): PBS, 0.05% BSA, 50% Glycerol, 0.02% Sodium azide.
Concentration: 0.25 mg/ml (Please refer to the vial label for the specific concentration.)
Background: This gene encodes the largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains a carboxy terminal domain composed of heptapeptide repeats that are essential for polymerase activity. These repeats contain serine and threonine residues that are phosphorylated in actively transcribing RNA polymerase. In addition, this subunit, in combination with several other polymerase subunits, forms the DNA binding domain of the polymerase, a groove in which the DNA template is transcribed into RNA. [provided by RefSeq, Jul 2008]
Uniprot ID: P24928
Antigen Species: Human
Immunogen: A phospho specific peptide corresponding to residues surrounding S5 of human POLR2A carboxy-terminal domain (CTD) heptapeptide repeat YSPTSPS.
Purification: Purified by affinity chromatography
Conjugation: Unconjugated
Full Name: RNA polymerase II subunit A
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