RS 25344 (hydrochloride), CAS 152815-28-6

Formulation: A solid

Formal Name: 1-(3-nitrophenyl)-3-(4-pyridinylmethyl)-pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione

Purity: ≥95%

Formula Markup: C19H13N5O4 • HCl

Formula Weight: 411,8

Shelf life (days): 1460

CAS Number: 152815-28-6

Notes: RS 25344 is an inhibitor of phosphodiesterase 4 (PDE4; IC50 = 0.3 nM).{64985} It is selective for PDE4 over PDE1, -2, and -3 (IC50s = >100 µM for all). RS 25344 inhibits concanavalin A-induced IL-5 release and LPS-induced TNF-α release in isolated human peripheral blood mononuclear cells (PBMCs; EC50s = 0.3 and 5.4 nM, respectively).{64986}

• SKU: CAY37793-100
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 37793-100
• Package Unit: 100 mg
• Quantity Unit: STK
• Application: Reinstoffe