RUVBL1/2 ATPase-IN-1, CAS 423128-55-6

Product Description: RUVBL1/2 ATPase-IN-1 (compound 18) is a potent and selective inhibitor of RUVBL1/2 ATPase with IC50 values of 6.0 and 7.7 μM, respectively. RUVBL1 and RUVBL2 are highly conserved AAA ATPases (ATPases Associated with various cellular Activities) and highly relevant to the progression of cancer. RUVBL1/2 ATPase-IN-1 has the potential for the research of cancer diseases[1].

Applications: Cancer-programmed cell death

Formula: C28H28F3N5O

References: [1]Zhang G, et al. Discovery of small-molecule inhibitors of RUVBL1/2 ATPase. Bioorg Med Chem. 2022;62:116726.

CAS Number: 423128-55-6

Molecular Weight: 507.55

Compound Purity: 99.63

Research Area: Cancer

Solubility: DMSO : 10 mg/mL (ultrasonic;warming;heat to 60°C)

Target: Proton Pump

• SKU: MEXHY-146074-100
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-146074-100
• Package Unit: 100 mg
• Quantity Unit: STK