Product Description: S-Adenosyl-L-methionine tosylate is produced endogenously from methionine and ATP by action of the enzyme methionine adenosyltransferase and is an important orally active methyl group donor. S-Adenosyl-L-methionine tosylate is a dietary supplement with potent antidepressant and analgesic effects, and has the potential for liver disease and osteoarthritis research[1][2][3].
Applications: COVID-19-immunoregulation
Formula: C22H30N6O8S2
Citations: Environ Sci Technol. 2025 Jan 2./Nat Commun. 2024 Nov 12;15(1):9529./Biochem Pharmacol. 2023 Dec 6:219:115967./bioRxiv. 2023 Jun 1./Epigenetics Chromatin. 2021 Dec 4;14(1):52./Int Immunopharmacol. 2021 Mar 22;95:107545./J Agric Food Chem. 2021 Jul 30./Research Square Preprint. 2020 Aug./Research Square Preprint. 2021 Jun./J Cell Physiol. 2024 Oct 6:e31452./Molecules. 2023 Apr 11, 28(8), 3375./J Pharm Biomed Anal. 2024 Jan 20, 115991./Pharmacol Res. 2024 Sep 16:107420.
References: [1]G M Bressa. et al. S-adenosyl-l-methionine (SAMe) as antidepressant: meta-analysis of clinical studies. Acta Neurol Scand Suppl. 1994;154:7-14./[2]Wadie I Najm, et al. S-adenosyl methionine (SAMe) versus celecoxib for the treatment of osteoarthritis symptoms: a double-blind cross-over trial. [ISRCTN36233495]. BMC Musculoskelet Disord. 2004 Feb 26;5:6./[3]Shelly C Lu, et al. S-adenosylmethionine in liver health, injury, and cancer. Physiol Rev. 2012 Oct;92(4):1515-42.
CAS Number: 52248-03-0
Molecular Weight: 570.64
Compound Purity: 99.01
Research Area: Cancer; Inflammation/Immunology; Neurological Disease
Solubility: H2O : 150 mg/mL (ultrasonic)
Target: Apoptosis;Endogenous Metabolite
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