(S)-(+)-Ibuprofen-d3, CAS 1329643-44-8

Product Description: (S)-(+)-Ibuprofen-d3 is a deuterium labeled (S)-(+)-Ibuprofen. (S)-(+)-Ibuprofen is the S(+)-enantiomer of Ibuprofen that inhibits COX-1 and COX-2 activity with IC50s of 2.1 μM and 1.6 μM. (S)-(+)-Ibuprofen has analgesic, antiinflammatory and antipyretic effects[1][2].

Applications: COVID-19-immunoregulation

Formula: C13H15D3O2

References: [1]Evans AM, et al. Comparative pharmacology of S(+)-ibuprofen and (RS)-ibuprofen. Clin Rheumatol. 2001 Nov;20 Suppl 1:S9-14./[2]Xu HR, et al. The effect of CYP2C19 activity on pharmacokinetics of lansoprazole and its active metabolites in healthy subjects. Pharm Biol. 2010 Aug;48(8):947-52.

CAS Number: 1329643-44-8

Molecular Weight: 209.30

Compound Purity: 98.87

Research Area: Inflammation/Immunology

Solubility: 10 mM in DMSO/DMSO : 100mg/mL (ultrasonic)/Ethanol : 100mg/mL (ultrasonic)

Target: COX

• SKU: MEXHY-78131AS-5
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-78131AS-5
• Package Unit: 5 mg
• Quantity Unit: STK