Clone Name: SPM354
Light Chain: Kappa
Application Note: WB: 1-2 μg/ml. ICC/IF: 1-2 μg/ml. IHC-P: 1-2 μg/ml. FACS: 1-2μg/1x10⁶ cells. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 12.11.2024
Form: Liquid
Buffer (with preservative): 10mM PBS, 0.05% BSA (Please contact us for PBS only format), 0.05% Sodium azide.
Concentration: 0.2 mg/ml (Please refer to the vial label for the specific concentration.)
Background: The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21; however, this gene is located at 21q22.3. This protein may function in Neurite extension, proliferation of melanoma cells, stimulation of Ca2+ fluxes, inhibition of PKC-mediated phosphorylation, astrocytosis and axonal proliferation, and inhibition of microtubule assembly. Chromosomal rearrangements and altered expression of this gene have been implicated in several neurological, neoplastic, and other types of diseases, including Alzheimer's disease, Down's syndrome, epilepsy, amyotrophic lateral sclerosis, melanoma, and type I diabetes. [provided by RefSeq, Jul 2008]
Uniprot ID: P04271
Antigen Species: Bovine
Immunogen: Purified bovine brain S100 protein
Purification: Protein A/G purified
Conjugation: Unconjugated
Full Name: S100 calcium binding protein B
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