SABRAC, CAS 886212-98-2

Formulation: A solid

Formal Name: 2-bromo-N-[(1S,2R)-2-hydroxy-1-(hydroxymethyl)heptadecyl]-acetamide

Purity: ≥95%

Formula Markup: C20H40BrNO3

Formula Weight: 422,4

Shelf life (days): 730

CAS Number: 886212-98-2

Notes: SABRAC is an inhibitor of acid ceramidase (IC50 = 52 nM).{57893} It is selective for acid ceramidase over neutral ceramidase and the cysteine protease papain at 3 µM. SABRAC inhibits acid ceramidase in PC3 MC metastatic prostate cancer cells (IC50 = <1 µM), as well as induces accumulation of ceramides in the same cells. It completely inhibits anchorage-independent colony formation but does not induce cytotoxicity in PC3 MC cells when used at a concentration of 5 µM.

• SKU: CAY9003925-1
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 9003925-1
• Green Labware: No
• Package Unit: 1 mg
• Quantity Unit: STK
• Application: Reinstoffe