SB-431542, CAS 301836-41-9

Description: SB-431542 is an inhibitor of ALK5/TGF-β type I Receptor (IC50=94 nM) and is selective. SB 431542 also has inhibitory activity against ALK4 and ALK7 but not other proteins. SB 431542 can be used for induced differentiation of stem cells.

CAS Number: 301836-41-9

Formula: C22H16N4O3

Molecular Weight: 384,39

References: Halder SK, et al. A specific inhibitor of TGF-beta receptor kinase, SB-431542, as a potent antitumor agent for human cancers. Neoplasia. 2005 May;7(5):509-21.

• SKU: TGMT1726-1mL
• Manufacturer: TargetMol Chemicals
• Manufacturer SKU: T1726-1mL
• Package Unit: 1 mL
• Quantity Unit: STK