Product Type: Inhibitor
CAS No.: 301836-41-9
MolecularFormula: C22H16N4O3
Molecular Weight: 384,4
Source: Synthetic
Purity: ≥98% (HPLC)
Solubility: Soluble to 10 mM in ethanol and to 100 mM in DMSO
Appearance: Yellow solid
PubChem CID: 4521392
Scientific Background: SB431542 is a potent and selective inhibitor of the transforming growth factor-β (TGF-β) type I receptor, activin receptor-like kinases. It has been shown to inhibit ALK4, 5, and 7.
References: 1. Laping N.J., et al. (2002) Mol. Pharm. 62(1): 58–64.
Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.