SC 514, CAS 354812-17-2

IKK-2 kinase inhibitor

Product Type: Inhibitor

CAS No.: 354812-17-2

MolecularFormula: C9H8N2OS2

Molecular Weight: 224,3

Source: Synthetic

Purity: ≥98% (TLC)

Solubility: Soluble in DMSO (>25 mg/ml)

Appearance: Yellow solid

PubChem CID: 2807869

Scientific Background: SC 514 is a selective and reversible inhibitor of IκB kinase 2 / IKKβ (IKK-2). It has been shown to displays > 10-fold selectivity over 28 other kinases including JNK, p38, MK2 and ERK. SC-514 exhibits anti-inflammatory properties. SC 514 is cell permeable.

References: 1. Kishore N., et al. (2003) J. Biol. Chem. 278(35): 32861–32871. 2. Baxter A., et al. (2004) Bioorganic Med. Chem. Letters. 14(11): 2817–2822.

Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

• SKU: STRSIH-475-50MG
• Manufacturer: Stressmarq Biosciences
• Manufacturer SKU: SIH-475-50MG
• Green Labware: No
• Package Unit: 50 mg
• Quantity Unit: STK