SC 79, CAS 305834-79-1

Akt kinase activator

Product Type: Activator

CAS No.: 305834-79-1

MolecularFormula: C17H17ClN2O5

Molecular Weight: 364,8

Source: Synthetic

Purity: 98% (TLC); NMR (Conforms)

Solubility: May be dissolved in DMSO (100mg/mL); or ethanol (40mg/mL, warm)

Appearance: White solid

Scientific Background: SC 79 is an activator of Akt (protein kinase B). Specifically, it has been shown to bind the plecktrin homology (PH) domain of Akt. This mimics the binding of Phosphatidylinositol (3,4,5)-trisphosphates, which induces a conformational change in Akt, that enhances phosphorylation and activation.

References: 1. Jo H., et al. (2012) Pro. Nat. Acad. Sci. USA. 109(26): 10581–10586.

Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

• SKU: STRSIH-512-5MG
• Manufacturer: Stressmarq Biosciences
• Manufacturer SKU: SIH-512-5MG
• Green Labware: No
• Package Unit: 5 mg
• Quantity Unit: STK