Conjugation: HRP: Horseradish Peroxidase
Description of Target: SFN is an adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathway. SFN binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. When bound to KRT17, SFN regulates protein synthesis and epithelial cell growth by stimulating Akt/mTOR pathway.
Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SFN
Key Reference: Yang,W., (2008) Cell Cycle 7 (5), 670-682
Molecular Weight: 28kDa
Peptide Sequence: Synthetic peptide located within the following region:
FHYEIANSPEEAISLAKTTFDEAMADLHTLSEDSYKDSTLIMQLLRDNLTProduct Format: Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.
Protein Name: 14-3-3 protein sigma
Protein Size: 248
Purification: Affinity Purified