Application Note: WB: 0.25-0.5μg/ml. ICC/IF: 2μg/ml. IHC-P: 0.5-1μg/ml. FACS: 1-3μg/1x106 cells. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 49
Form: Liquid
Buffer (with preservative): 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg sodium azide.
Concentration: 0.5 mg/ml (Please refer to the vial label for the specific concentration.)
Background: This gene encodes a serine/threonine protein kinase that plays an important role in cellular stress response. This kinase activates certain potassium, sodium, and chloride channels, suggesting an involvement in the regulation of processes such as cell survival, neuronal excitability, and renal sodium excretion. High levels of expression of this gene may contribute to conditions such as hypertension and diabetic nephropathy. Several alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Jan 2009]
Uniprot ID: O00141
Antigen Species: Human
Immunogen: A synthetic peptide corresponding to a sequence of human SGK1 (AILIAFMKQRRMGLNDFIQKIAN).
Purification: Purified by antigen-affinity chromatography
Conjugation: Unconjugated
Full Name: serum/glucocorticoid regulated kinase 1