Clone Name: SZ04-01
Application Note: WB: 1:1000-1:5000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 82
Form: Liquid
Buffer (with preservative): 1x TBS (pH7.4), 1% BSA, 40% Glycerol, 0.05% Sodium azide.
Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration.)
Background: This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2008]
Uniprot ID: Q96EB6
Antigen Species: Human
Immunogen: Recombinant protein
Purification: Protein A purified
Conjugation: Unconjugated
Full Name: sirtuin 1