Target: Slo2.2
Conjugate: APC
Product Type: Monoclonal
Clone Number: N3/26 (Formerly sold as S3-26)
Immunogen: Fusion protein amino acids 1168-1237 of rat Slo2.2 (Slack)
Swiss-Prot: Q9Z258
Purification: Protein G Purified
Storage Buffer: PBS pH7.4, 50% glycerol, 0.09% sodium azide *Storage buffer may change when conjugated
Concentration: 1 mg/ml
Specificity: Detects ~140kDa. Weak human detection. Does not cross-react with KCNT2/Slo2.1/Slick.
Cellular Localization: Cell Membrane
Scientific Background: Slo2.2 is a novel member of the mammalian Slo potassium channel gene family. Slo2 channels may contribute to the resting potentials of cells that control their basal level of excitability (1). They also have sensors that couple channel activity to the intracellular concentrations of Na+ and Cl- (2).
References: 1. Santi C.M., et al. (2006) J Neuroscience, 26(19): 5059-5068.2. Yuan A., et al. (2003) Neuron 37: 765-773.
Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
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