SMO (Smoothened Homolog)

SMO (Smoothened Homolog), IgG

Background: SMO is a G protein-coupled receptor (GPCR) that putatively associates with the patched protein (PTCH) to transduce the hedgehog's proteins signal. The binding of sonic hedgehog (SHH) to its receptor patched is thought to prevent normal inhibition by patched of smoothened (SMO). In basal cell carcinoma there are two somatic mutations SMO, D473-> H473 and R562 ->Q562.

Positive Control: Brain.

Immunogen: peptide immunogen.

Formulation: Provided as solution in phosphate buffered saline with 0.08% sodium azide.

UniProt: Q99835 (Human).

Caution: This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals.

• SKU: EXAX2377B
• Manufacturer: Exalpha Biologicals Inc
• Manufacturer SKU: X2377B
• Green Labware: No
• Package Unit: 50 µg
• Quantity Unit: STK
• Reactivity: Human
• Application: Western Blotting
• Isotype: IgG
• Host: Rabbit