Sphingosine, CAS 123-78-4

Protein Kinase C inhibitor

Product Type: Inhibitor

CAS No.: 123-78-4

MolecularFormula: C18H37NO2

Molecular Weight: 299,49

Source: Synthetic

Purity: >98%

Solubility: Soluble to 100 mM in DMSO

Appearance: Solid

PubChem CID: 5280335

Scientific Background: Sphingosine can be phosphorylated in vivo via two kinases which leads to the formation of a potent signaling lipid. It is a selective inhibitor of protein kinase C, but does not inhibit protein kinase A or myosin light chain kinase. It also inhibits calmodulin-dependent enzymes and is the precursor of ceramide.

References: 1. Radin N. (2003) Biochem J. 371(Pt2): 243-256.2. Carter H.E., Glick F.J., Norris W.P., Phillips G.E. (1947) J Biol Chem. 170: 285-295.

Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

• SKU: STRSIH-202-100MG
• Manufacturer: Stressmarq Biosciences
• Manufacturer SKU: SIH-202-100MG
• Package Unit: 100 mg
• Quantity Unit: STK
• Reactivity: Human