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Applications: The monoclonal neutralizing IgG can be used for functional assays to block SARS-CoV-2 Spike protein and ACE2 binding.
Assay Conditions: See datasheet for detailed information.
Clone Number: Clone G10xA5
Description: This monoclonal antibody recognizes the SARS-CoV-2 Spike RBD (B.1.1.529, Omicron Variant) protein and neutralizes its interaction with ACE2 [Table of Variants]. The human ACE2 receptor is found on the surface of type I and II pneumocytes, endothelial cells, and ciliated bronchial epithelial cells. ACE2 is known to mediate COVID-19 infection through direct binding of the SARS-CoV-2 Spike protein. This neutralizing antibody has been functionally tested using the Spike S1 RBD (B.1.1.529, Omicron Variant) (SARS-CoV-2): ACE2 Inhibitor Screening Colorimetric Assay Kit (BPS Bioscience, #78339).
Format: Aqueous buffer solution
Formulation: 1X PBS, 0.2% BSA
Purification: Protein A affinity chromatography
Storage Stability: Store in aliquots at -20°C. Stable for at least 6 months from date of receipt.
Warnings: Avoid freeze/thaw cycles.
Biosafety Level: Not applicable (BSL-1)
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