SPOP-IN-1, CAS 2136270-56-7

Product Description: SPOP-IN-1 is a selective SPOP E3 ubiquitin ligase inhibitor. SPOP-IN-1 leads to the accumulation of tumor suppressors PTEN and DUSP7 and decreased levels of phosphorylated AKT and ERK in clear-cell renal cell carcinoma[1].

Applications: Cancer-Kinase/protease

Formula: C26H31N7O2S

References: [1]Dong Z, et al. Structure-Activity Relationship of SPOP Inhibitors against Kidney Cancer. J Med Chem. 2020 May 14;63(9):4849-4866.

CAS Number: 2136270-56-7

Molecular Weight: 505.64

Compound Purity: 99.71

Research Area: Cancer

Solubility: DMSO : 5 mg/mL (ultrasonic;warming;heat to 60°C)

Target: Akt;E1/E2/E3 Enzyme;ERK

• SKU: MEXHY-156382-10
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-156382-10
• Package Unit: 10 mg
• Quantity Unit: STK