Formulation: A solid
Formal Name: (S)-2-(((S)-2-((6S,9S,18S, 21S,24S)-1- amino-6-(((S)- 2-((S)-3- amino-2- oxobutanoyl) pyrrolidin-1- yl)amino)-21- (4-amino butyl)-9- benzyl-24- (3-guanidino propyl)-1- imino-18- isopropyl-7, 10,13,16,19, 22,25-hepta oxo-2,8,11,14, 17,20,23-hepta azahexacosan- 26-oyl) pyrrolidin-1- yl)amino)-N1- ((6S,9S,12S)- 1,17-diamino- 9-(4-hydroxy benzyl)-6-(2- ((S)-1-hydroxy pyrrolidin- 2-yl)-2-oxo acetyl)-1,17- diimino-8,11- dioxo-2,7,10, 16-tetraaza heptadecan-12- yl)succinimide, trifluoroacetate salt
Purity: ≥98%
Formula Markup: C79H127N29O18 • XCF3COOH
Formula Weight: 1771,1
Shelf life (days): 1460
Notes: ssK36 is a peptide super-substrate for the histone methyltransferase SET domain-containing protein 2 (SETD2) corresponding to amino acids 29-43 of histone H3 lysine 36 (H3K36) with amino acid substitutions at positions 31, 32, 36, 37, and 39.{67510} ssK36 is methylated 70-fold more and 290-fold faster than H3K36 (29-43) in cell-free assays.
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