Application Note: WB: 1:4000-1:6000. ICC/IF: 1:5000. IHC-P: 1:2500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 39
Form: Liquid
Buffer (with preservative): Whole serum, no preservatives.
Concentration:
Background: Somatostatin and its related peptide cortistatin exert multiple biological actions on normal and tumoral tissue targets by interacting with somatostatin receptors (SSTRs). The protein encoded by this gene is one of the SSTRs, which is a multi-pass membrane protein and belongs to the G-protein coupled receptor 1 family. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase, and different regions of this receptor molecule are required for the activation of different signaling pathways. A mutation in this gene results in somatostatin analog resistance. Alternatively spliced transcript variants have been identified in this gene.[provided by RefSeq, Feb 2010]
Uniprot ID: P35346
Antigen Species: Human
Immunogen: Synthetic peptide corresponding to residues Q(344) E A T R P A H R A A A N G L M Q T S K L(364) of human SSTR5.
Purification: Unpurified
Conjugation: Unconjugated
Full Name: somatostatin receptor 5
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