Abbreviation: SULF2
Target Synonym: SULF2;HSULF-2
Conjugation: Unconjugated
UNIProt ID: Q8IWU5
Background: Heparan sulfate proteoglycans (HSPGs) act as coreceptors for numerous heparin-binding growth factors and cytokines and are involved in cell signaling. Heparan sulfate 6-O-endosulfatases, such as SULF2, selectively remove 6-O-sulfate groups from heparan sulfate. This activity modulates the effects of heparan sulfate by altering binding sites for signaling molecules (Dai et al., 2005 [PubMed 16192265]).[supplied by OMIM, Mar 2008]
Concentration: 1mg/mL
Immunogen: Recombinant fusion protein of human SULF2
Dilution: WB 1:500-1:2000