Conjugation: FITC: Fluorescein Isothiocyanate
Description of Target: SUMO proteins, such as SUMO3, and ubiquitin (see MIM 191339) posttranslationally modify numerous cellular proteins and affect their metabolism and function. However, unlike ubiquitination, which targets proteins for degradation, sumoylation participates in a number of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability.SUMO proteins, such as SUMO3, and ubiquitin (see MIM 191339) posttranslationally modify numerous cellular proteins and affect their metabolism and function. However, unlike ubiquitination, which targets proteins for degradation, sumoylation participates in a number of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability (Su and Li, 2002 [PubMed 12383504]).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SUMO3
Key Reference: Zhang,X.D., (2008) Mol. Cell 29 (6), 729-741
Molecular Weight: 12kDa
Peptide Sequence: Synthetic peptide located within the following region:
MRQIRFRFDGQPINETDTPAQLEMEDEDTIDVFQQQTGGVPESSLAGHSFProduct Format: Liquid. Purified antibody supplied in 1x PBS buffer.
Protein Name: Small ubiquitin-related modifier 3
Protein Size: 103
Purification: Affinity Purified
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