Targefrin, CAS 3031514-44-7

Product Description: Targefrin is a potent EphA2-targeting agent, acts as an antagonist. Targefrin binds EphA2-LBD with 21 nM dissociation constant and an IC50 value of 10.8 nM. Targefrin induces cellular receptor internalization and degradation in several pancreatic cancer cell lines[1].

Applications: Cancer-Kinase/protease

Formula: C85H116F3N19O15

References: [1]Baggio C, Udompholkul P, Gambini L, Pellecchia M. Targefrin: A Potent Agent Targeting the Ligand Binding Domain of EphA2. J Med Chem. 2022 Nov 4.

CAS Number: 3031514-44-7

Molecular Weight: 1700.94

Compound Purity: 99.45

Research Area: Cancer

Solubility: DMSO : 100 mg/mL (ultrasonic)

Target: Ephrin Receptor

• SKU: MEXHY-P3717-5
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-P3717-5
• Green Labware: No
• Package Unit: 5 mg
• Quantity Unit: STK