Tat-ASIC1a (1-20) (mouse, rat) (trifluoroacetate salt)

Formulation: A solid

Purity: ≥95%

Formula Markup: C150H265N55O47S2 • XCF3COOH

Formula Weight: 3655,2

Shelf life (days): 1460

Notes: Tat-ASIC1a (1-20) is a synthetic peptide composed of the cell-penetrating peptide sequence from the HIV-1 Tat protein transduction domain linked to a 20-amino acid peptide corresponding to amino acids 1-20 of acid-sensing ion channel 1a (ASIC1a).{51581} It prevents acid-induced association of ASIC1a with receptor-interacting serine/threonine kinase 1 (RIPK1) and necroptosis in primary mouse cortical neurons when used at a concentration of 10 µM. Tat-ASIC1a (1-20) decreases infarct volume in a mouse model of ischemia induced by middle cerebral artery occlusion (MCAO).

• SKU: CAY37501-10
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 37501-10
• Green Labware: No
• Package Unit: 10 mg
• Quantity Unit: STK