Taxol, CAS 33069-62-4

Microtubule stabilizer

Product Type: Inducer

CAS No.: 33069-62-4

MolecularFormula: C47H51NO14

Molecular Weight: 853,9

Source: Synthetic

Purity: >98% (TLC); NMR (Conforms)

Solubility: Soluble in DMSO, ethanol or acetonitrile

Appearance: White solid

PubChem CID: 36314

Scientific Background: Paclitaxel is a mitotic inhibitor that promotes and stabilizes tubulin polymerization, causing cell cycle arrest (1). Induces autocatalytic activation of caspase-10 in CCRF-HSB-2 cells, triggering apoptosis (2).

References: 1. Wani M., Taylor H., Wall M., Coggon P., and McPhail A. (1971) J Am Chem Soc. 93(9): 2325-2327.2. Park S.J., et al. (2004) J Biol Chem. 279(49): 51057-51067.

Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

• SKU: STRSIH-239-50MG
• Manufacturer: Stressmarq Biosciences
• Manufacturer SKU: SIH-239-50MG
• Package Unit: 50 mg
• Quantity Unit: STK