TCO-GK-PEG4-NHS ester, CAS 2307311-19-7

Product Description: TCO-GK-PEG4-NHS ester is an ADC Linker, and can be used for synthesis of [18F]AlF-NOTA-Tz-TCO-GK-2Rs15d. [18F]AlF-NOTA-Tz-TCO-GK-2Rs15d binds with high affinity and immunoreactivity to HER2[1]. TCO-GK-PEG4-NHS ester is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.

Applications: Cancer-programmed cell death

Formula: C33H52N4O14

References: [1]Zhou Z, et al. An Efficient Method for Labeling Single Domain Antibody Fragments with 18F Using Tetrazine- Trans-Cyclooctene Ligation and a Renal Brush Border Enzyme-Cleavable Linker. Bioconjug Chem. 2018 Dec 19;29(12):4090-4103.

CAS Number: 2307311-19-7

Molecular Weight: 728.78

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: ADC Linker

• SKU: MEXHY-154802-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-154802-0
• Green Labware: No
• Package Unit: Get quote
• Quantity Unit: STK