TCO-PEG4-NHS ester, CAS 1613439-69-2

Product Description: TCO-PEG4-NHS ester is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. TCO-PEG4-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. TCO-PEG4-NHS ester is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.

Applications: Cancer-programmed cell death

Formula: C24H38N2O10

References: [1]Jung S, et al. An integrated approach for enhanced protein conjugation and capture with viral nanotemplatesand hydrogel microparticle platforms via rapid bioorthogonal reactions. Langmuir. 2014 Jul 8;30(26):7762-70.

CAS Number: 1613439-69-2

Molecular Weight: 514.57

Compound Purity: 99.58

Research Area: Cancer

Solubility: DMSO : 50 mg/mL (ultrasonic)

Target: ADC Linker;PROTAC Linkers

• SKU: MEXHY-141167-5
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-141167-5
• Green Labware: No
• Package Unit: 5 mg
• Quantity Unit: STK