Terazosin Hydrochloride, CAS 63074-08-8

Alpha adrenergic antagonist, and Hsp90 Activator

Product Type: Antagonist

CAS No.: 63074-08-8

MolecularFormula: C19H25N5O4·HCl

Molecular Weight: 423,89

Source: Synthetic

Purity: >98%

Solubility: Soluble to 20mg/ml in warm water

Appearance: White to off-white solid

PubChem CID: 44383

Scientific Background: Terazosin (TZ) which is marketed as an alpha1-adrenergic receptor antagonist, has been shown to alleviate organ damaged and increase survival in rodent models of sepsis and stroke in vivo (1). It inhibits apoptosis in macrophages by activation of Pgk1 and Hsp90 (1).

References: 1. Chen X., et al. (2015) Nature Chem Biol. 11:19-25.2. Hancock A.A., et al. (1995) J Recept Signal Transduct Res. 15: 863.3. Kyncl J.J. (1986) Am J Med. 80:12.

Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

• SKU: STRSIH-516-100MG
• Manufacturer: Stressmarq Biosciences
• Manufacturer SKU: SIH-516-100MG
• Green Labware: No
• Package Unit: 100 mg
• Quantity Unit: STK