Application Note: WB: 0.5-2μg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 39
Positive Control: The peptide used to generate this antibody is available for purchase (GTX89915-PEP).
Specificity/Sensitivity: This antibody is expected to recognise both reported Human isoforms according to NP_036384.1 and NP_001018068.1.
Form: Liquid
Buffer (with preservative): TBS, 0.5% BSA, 0.02% Sodium azide.
Concentration: 0.50 mg/ml (Please refer to the vial label for the specific concentration.)
Background: This gene encodes a member of the micropthalmia (MiT) family of basic helix-loop-helix leucine zipper transcription factors. MiT transcription factors regulate the expression of target genes by binding to E-box recognition sequences as homo- or heterodimers, and play roles in multiple cellular processes including survival, growth and differentiation. The encoded protein is a transcriptional activator of the nonmuscle myosin II heavy chain-A gene, and may also co-regulate target genes in osteoclasts as a heterodimer with micropthalmia-associated transcription factor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011]
Uniprot ID: O14948
Antigen Species: Human
Immunogen: Peptide with sequence TLDHQIINPTLK-C, from the N Terminus of the protein sequence according to NP_036384.1; NP_001018068.1.
Purification: Purified by ammonium sulphate precipitation followed by antigen affinity chromatography
Conjugation: Unconjugated
Full Name: transcription factor EC
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