Thalidomide-Piperazine 5-fluoride (hydrochloride), CAS 2222114-23-8

Product Description: Thalidomide-Piperazine 5-fluoride hydrochloride is a derivative of cereblon (CRBN) inhibitor Thalidomide (HY-14658), which can be used as ligands for E3 ubiquitin ligase (Ligands for E3 Ligase) for PROTACs Synthesis[1].

Applications: Cancer-programmed cell death

Formula: C17H18ClFN4O4

References: [1]Fischer ES, et al. Structure of the DDB1-CRBN E3 ubiquitin ligase in complex with thalidomide. Nature. 2014 Aug 7;512(7512):49-53.

CAS Number: 2222114-23-8

Molecular Weight: 396.80

Compound Purity: 98.91

Research Area: cancer

Solubility: 10 mM in DMSO

Target: Apoptosis;Autophagy;E3 Ligase Ligand-Linker Conjugates

• SKU: MEXHY-W145436-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-W145436-0
• Package Unit: Get quote
• Quantity Unit: STK