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Encompassing Amino Acids: 22-191
Description: Mouse TIM-3, also known as T-cell immunoglobulin mucin receptor 3, T-cell membrane protein 3, TIMD-3, Hepatitis A virus cellular receptor 2, HAVCR-2, and KIM-3. GenBank Accession No. NM_032782, a.a. 22-191, expressed in a HEK293 cells expression system. This protein is fused at the C-terminus to the Fc region of human IgG1 and is enzymatically biotinylated using Avi-tag™ technology. MW = 47 kDa. This protein runs at a higher MW by SDS-PAGE due to glycosylation.
Format: Aqueous buffer solution.
Formulation: 8 mM Phosphate, pH 7.4, 110 mM NaCl, 2.2 mM KCl, and 20% glycerol.
Genbank: NM_032782
Purity: ≥90%
Storage Stability: At least 6 months at -80°C.
Tags: C-terminal Fc-Avi-Tag, Biotin-Labeled
Warnings: Avoid freeze/thaw cycles. Protein may be diluted to ≥100 µg/ml in PBS + glycerol and stored at -80°C.
Biosafety Level: Not applicable (BSL-1)
References: 1. Zhu, C. et al., Nat. Immunol. 2005; 6:1245-12525.2. Anderson, A.C. et al., Science. 2007; 318(5853):1141-1143.
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