Tirabrutinib, CAS 1351636-18-4

Description: Tirabrutinib (GS-4059) (ONO-4059) is an orally active Bruton’s Tyrosine Kinase (Btk) inhibitor (can cross the blood-brain barrier (BBB)), with an IC50 of 6.8 nM. Tirabrutinib irreversibly and covalently binds to Btk and inhibits aberrant B cell receptor signaling. Tirabrutinib can be used in studies of autoimmune diseases and hematological malignancies.

CAS Number: 1351636-18-4

Formula: C25H22N6O3

Molecular Weight: 454,48

References: Dhillon S. Tirabrutinib: First Approval. Drugs. 2020 Jun;80(8):835-840.

• SKU: TGMTQ0236-200mg
• Manufacturer: TargetMol Chemicals
• Manufacturer SKU: TQ0236-200mg
• Package Unit: 200 mg
• Quantity Unit: STK