Tivozanib, CAS 475108-18-0

Product Description: Tivozanib (AV-951; KRN951) is a selective, orally active inhibitor for vascular endothelial growth factor receptor (VEGFR)-1, 2 3, with IC50s of 30, 6.5 and 15 nM, respectively. Tivozanib exhibits antitumor efficacy[1].

Applications: Cancer-Kinase/protease

Formula: C22H19ClN4O5

References: [1]Nakamura K, et al., KRN951, a highly potent inhibitor of vascular endothelial growth factor receptor tyrosine kinases, has antitumor activities and affects functional vascular properties. Cancer Res. 2006 Sep 15;66(18):9134-42.

CAS Number: 475108-18-0

Molecular Weight: 454.86

Compound Purity: 99.60

Research Area: Cancer

Solubility: DMSO : 25 mg/mL (ultrasonic)

Target: VEGFR

• SKU: MEXHY-10977-200
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-10977-200
• Package Unit: 200 mg
• Quantity Unit: STK