TJ-M2010-5, CAS 1357471-57-8

Product Description: TJ-M2010-5 is a MyD88 inhibitor that binds to the TIR domain of MyD88 to interfere with its homodimerization, and the TLR/MyD88 signal pathway[1][2]. TJ-M2010-5 can be used for the research of myocardial ischemia/reperfusion injury (MIRI)[2].

Applications: Neuroscience-Neuromodulation

Formula: C23H26N4OS

References: [1]Lin Xie, et al. Targeting of MyD88 Homodimerization by Novel Synthetic Inhibitor TJ-M2010-5 in Preventing Colitis-Associated Colorectal Cancer. J Natl Cancer Inst. 2015 Dec 28;108(4):djv364./[2]Yan Miao,et al. Inhibition of MyD88 by a novel inhibitor reverses two-thirds of the infarct area in myocardial ischemia and reperfusion injury.Am J Transl Res. 2020 Sep 15;12(9):5151-5169.

CAS Number: 1357471-57-8

Molecular Weight: 406.54

Compound Purity: 99.85

Research Area: Cardiovascular Disease

Solubility: DMSO : 100 mg/mL (ultrasonic)

Target: MyD88

• SKU: MEXHY-139397-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-139397-10.1
• Package Unit: 10mM/1mL
• Quantity Unit: STK