Clone Name: MT11B10
Application Note: *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 26
Specificity/Sensitivity: This antibody is able to detect native and recombinant mouse TNF-α.
Form: Liquid
Buffer (with preservative): PBS, 0.02% Sodium azide.
Concentration: 0.5 mg/ml (Please refer to the vial label for the specific concentration.)
Background: This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. Members of this family are classified based on primary sequence, function, and structure. This protein is synthesized as a type-II transmembrane protein and is reported to be cleaved into products that exert distinct biological functions. It plays an important role in the innate immune response as well as regulating homeostasis but is also implicated in diseases of chronic inflammation. In mouse deficiency of this gene is associated with defects in response to bacterial infection, with defects in forming organized follicular dendritic cell networks and germinal centers, and with a lack of primary B cell follicles. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2013]
Uniprot ID: P06804
Antigen Species: Mouse
Immunogen: Recombinant mouse TNF-α
Purification: Protein G purified
Conjugation: Biotin
Full Name: tumor necrosis factor
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