Product Description: Triphenyl phosphate is an organic phosphate flame retardant. Triphenyl phosphate can disrupt placental tryptophan metabolism by activating MAOA/ROS/NFκB, leading to abnormal neurological behavior. Triphenyl phosphate promotes oxidative stress by inducing inflammatory factors like nuclear factor kappa B (NFκB), interleukin-6, and tumor necrosis factor α. Triphenyl phosphate can also cause allergic contact dermatitis[1][2].
Formula: C18H15O4P
References: [1]Xiaoxun Lu, et al. Triphenyl phosphate disrupts placental tryptophan metabolism by activating MAOA/ROS/NFκB. Sci Total Environ. 2023 Dec 15:904:166688./[2]J G Camarasa, et al. Allergic contact dermatitis from triphenyl phosphate. Contact Dermatitis. 1992 Apr;26(4):264-5.
CAS Number: 115-86-6
Molecular Weight: 326.28
Compound Purity: 99.67
Research Area: Inflammation/Immunology; Neurological Disease
Target: Interleukin Related;Monoamine Oxidase;NF-κB;Reactive Oxygen Species;TNF Receptor
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