TTLL12 Polyclonal Antibody, Rabbit

Abbreviation: TTLL12

Target Synonym: TTLL12; dJ526I14.2; tubulin tyrosine ligase like 12

Conjugation: Unconjugated

UNIProt ID: Q14166

Background: Negatively regulates post-translational modifications of tubulin, including detyrosination of the C-terminus and polyglutamylation of glutamate residues. Also, indirectly promotes histone H4 trimethylation at 'Lys-20' (H4K20me3. Probably by controlling tubulin and/or histone H4 post-translational modifications, plays a role in mitosis and in maintaining chromosome number stability. During RNA virus-mediated infection, acts as a negative regulator of the DDX58/RIG-I pathway by preventing MAVS binding to TBK1 and IKBKE.

Concentration: 1mg/mL

Immunogen: Recombinant fusion protein of human TTLL12

Dilution: WB 1:500-1:2000

• SKU: ELSE-AB-92358-60
• Manufacturer: Elabscience Biotechnology
• Manufacturer SKU: ELA-E-AB-92358-60
• Green Labware: No
• Package Unit: 60 µl
• Quantity Unit: STK
• Reactivity: Human
• Clonality: Polyclonal
• Application: Western Blotting
• Isotype: IgG
• Host: Rabbit