Tyrosinase-Related Protein-1 (TYRP-1) (Melanoma Marker)(TYRP1/3283), 1mg/mL

Tyrosinase-Related Protein-1 (TYRP-1) (Melanoma Marker)(TYRP1/3283), 1mg/mL
SKU
BTMBNUM3283-50
Packaging Unit
50 uL
Manufacturer
Biotium

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Description: Reacts with a 75 kDa melanocyte-specific gene product, identified as Tyrosinase-related protein-1 (TRP-1). It is involved in melanin synthesis. TRP1 is present on the melanosomal membranes of melanoma, normal melanocytes and nevi. Recent evidence suggests that TRP-1 is involved in maintaining stability of tyrosinase protein and modulating its catalytic activity. TRP-1 is also involved in maintenance of melanosome ultrastructure and affects melanocyte proliferation and cell death. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Conjugate: Purified, BSA-free

Concentration: 1 mg/mL

Storage buffer: PBS, no BSA, no azide

Product Origin: Animal - Mus musculus (mouse)

Clone: TYRP1/3283

Entrez Gene ID: 7306

Immunogen: A recombinant fragment (around aa 257-377) of human TYRP1 protein (exact sequence is proprietary)

Verified AB Applications: IHC (FFPE) (verified)

Z-Antibody Applications: IHC, FFPE (verified)
More Information
SKU BTMBNUM3283-50
Manufacturer Biotium
Manufacturer SKU BNUM3283-50
Package Unit 50 uL
Quantity Unit STK
Reactivity Human
Clonality Monoclonal
Application Immunohistochemistry
Isotype IgG2b kappa
Host Mouse
Conjugate Unconjugated
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