U0126, CAS 109511-58-2

Product Description: U0126 is a selective MAP Kinase inhibitor, displaying a preference for MEK-1 and MEK-2. It is known that U0126 binds to MEK in a noncompetitive manner compared to ATP. Studies suggest that U0126 antagonizes the transcription of AP-1, via the inhibition of MEK. In addition, U0126 has been observed to inhibit promoters containing an AP-1 response element, while in contrast having no effect on promoters that lack an AP-1 response group. U0126 is an activator of PGC-1, mtTFA and Nuclear Respiratory Factor.

CAS Number: 109511-58-2

Molecular Weight: 380.49

Structure: C18H16N6S2

Compound Purity: >99%

• SKU: CGSSM106-5
• Manufacturer: Cell Guidance Systems
• Manufacturer SKU: SM106-5
• Package Unit: 5 mg
• Quantity Unit: STK