Target: VAChT
Conjugate: Unconjugated
Product Type: Monoclonal
Clone Number: N6/38 (Formerly sold as S6-38)
Immunogen: Synthetic peptide amino acids 521-532 of human VAChT
Swiss-Prot: Q16572
Purification: Protein G Purified
Storage Buffer: PBS pH7.4, 50% glycerol, 0.09% sodium azide *Storage buffer may change when conjugated
Concentration: 1 mg/ml
Specificity: Detects ~56kDa.
Cellular Localization: Membrane
Scientific Background: VAChT is a member of the vesicular amine transporter (VMAT) family. The encoded transmembrane protein transports acetylcholine into secretory vesicle for release into the extracellular space. Acetylcholine (Ach) transport utilizes a proton gradient established by a vacuolar ATPase. This gene is located within the first intron of the choline acetyltransferase gene.
References: 1. Erickson J.D., Varoqui H. (2000) FASEB J. 14(15): 2450-2458.2. Weihe E., Tao-Cheng J.H., Schafer M.K., Erickson J.D., Eiden L.E. (1996) Proc Natl Acad Sci USA. 93(8): 3547-3552.
Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
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