Conjugation: HRP: Horseradish Peroxidase
Description of Target: VASH1 is the angiogenesis inhibitor. It inhibits migration, proliferation and network formation by endothelial cells as well as angiogenesis. This inhibitory effect is selective to endothelial cells as it does not affect the migration of smooth muscle cells or fibroblasts. VASH1 does not affect the proliferation of cancer cells in vitro, but inhibits tumor growth and tumor angiogenesis. It acts in an autocrine manner. VASH1 inhibits artery neointimal formation and macrophage infiltration. Western blots using two different antibodies against two unique regions of this protein target confirm the same apparent molecular weight in our tests.
Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human VASH1
Key Reference: Yoshinaga,K., (2008) Cancer Sci. 99 (5), 914-919
Molecular Weight: 41kDa
Peptide Sequence: Synthetic peptide located within the following region:
ATWERMWKHVAKIHPDGEKVAQRIRGATDLPKIPIPSVPTFQPSTPVPERProduct Format: Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.
Protein Name: Vasohibin-1
Protein Size: 365
Purification: Affinity Purified
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