Application Note: WB: 0.5-1.5μg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 98
Positive Control: The peptide used to generate this antibody is available for purchase (GTX89695-PEP).
Specificity/Sensitivity: This antibody is expected to recognize both reported isoforms (NP_006104.4; NP_001073343.1).
Form: Liquid
Buffer (with preservative): TBS, 0.5% BSA, 0.02% Sodium azide.
Concentration: 0.50 mg/ml (Please refer to the vial label for the specific concentration.)
Background: This gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. This gene product acts as a GEF preferentially for RhoG, RhoA, and to a lesser extent, RAC1, and it associates maximally with the nucleotide-free states of these GTPases. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
Uniprot ID: Q9UKW4
Antigen Species: Human
Immunogen: Peptide with sequence C-SGEQGTLKLPEK, from the internal region of the protein sequence according to NP_006104.4; NP_001073343.1.
Purification: Purified by ammonium sulphate precipitation followed by antigen affinity chromatography
Conjugation: Unconjugated
Full Name: vav guanine nucleotide exchange factor 3
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