Application Note: WB: 0.2-2.5 ug/ml. IHC-P: 2-10 ug/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 31
Positive Control: human B lymphoblast , human fetal heart , human fetal muscle
Form: Liquid
Buffer (with preservative): PBS, 2% Sucrose, 0.09% Sodium azide.
Concentration: 0.5-1 mg/ml (Please refer to the vial label for the specific concentration.)
Background: This gene encodes a voltage-dependent anion channel (VDAC), and belongs to the mitochondrial porin family. VDACs are small, integral membrane proteins that traverse the outer mitochondrial membrane and conduct ATP and other small metabolites. They are known to bind several kinases of intermediary metabolism, thought to be involved in translocation of adenine nucleotides, and are hypothesized to form part of the mitochondrial permeability transition pore, which results in the release of cytochrome c at the onset of apoptotic cell death. Alternatively transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Oct 2011]
Uniprot ID: Q9Y277
Antigen Species: Human
Immunogen: A synthetic peptide corresponding to a N-terminal region of Human VDAC3
Purification: Affinity Purified
Conjugation: Unconjugated
Full Name: voltage dependent anion channel 3
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