Application Note: WB: 1:500-1:2000. ICC/IF: 1:200. IHC-P: 1:50-1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 54
Form: Liquid
Buffer (with preservative): PBS pH 7.4, 150mM NaCl, no preservatives.
Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration.)
Background: This gene encodes a type III intermediate filament protein. Intermediate filaments, along with microtubules and actin microfilaments, make up the cytoskeleton. The encoded protein is responsible for maintaining cell shape and integrity of the cytoplasm, and stabilizing cytoskeletal interactions. This protein is involved in neuritogenesis and cholesterol transport and functions as an organizer of a number of other critical proteins involved in cell attachment, migration, and signaling. Bacterial and viral pathogens have been shown to attach to this protein on the host cell surface. Mutations in this gene are associated with congenital cataracts in human patients. [provided by RefSeq, Aug 2017]
Uniprot ID: P08670
Antigen Species: Human
Immunogen: A synthesized peptide derived from human VIM(Accession P08670), corresponding to amino acid residues R424-E466.
Purification: Purified by antigen-affinity chromatography
Conjugation: Unconjugated
Full Name: vimentin
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