von Willebrand Factor / Factor VIII Related-Ag (Endothelial Marker) (VWF/1465), 1mg/mL

von Willebrand Factor / Factor VIII Related-Ag (Endothelial Marker) (VWF/1465), 1mg/mL
SKU
BTMBNUM1465-50
Packaging Unit
50 uL
Manufacturer
Biotium

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Description: von Willebrand Factor (vWF) is a multimeric glycoprotein that is found in endothelial cells, plasma and platelets. It acts as a carrier protein for Factor VIII and promotes platelet adhesion and aggregation. vWF undergoes a variety of posttranslational modifications that influence the affinity and availability for Factor VIII, including cleavage of the propeptide and formation of N-terminal disulfide bonds. This antibody helps to establish the endothelial nature of some lesions of disputed histogenesis, e.g. Kaposi's sarcoma and cardiac myxoma. It is widely used for differentiating vascular lesions from those of other tissue differentiation within a panel of other vascular markers although not all tumors of endothelial differentiation contain this antigen.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Conjugate: Purified, BSA-free

Concentration: 1 mg/mL

Storage buffer: PBS, no BSA, no azide

Product Origin: Animal - Mus musculus (mouse)

Clone: VWF/1465

Entrez Gene ID: 7450

Immunogen: Recombinant fragment of human vWF protein (aa1815-1939) (exact sequence is proprietary)

Verified AB Applications: IHC (FFPE) (verified)/WB (verified)

Z-Antibody Applications: IHC, FFPE (verified)/WB (verified)
More Information
SKU BTMBNUM1465-50
Manufacturer Biotium
Manufacturer SKU BNUM1465-50
Package Unit 50 uL
Quantity Unit STK
Reactivity Human
Clonality Monoclonal
Application Western Blotting, Immunohistochemistry
Isotype IgG1
Host Mouse
Conjugate Unconjugated
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