Formulation: A crystalline solid
Formal Name: αE-(3-hydroxy-5-oxo-4-phenyl-2(5H)-furanylidene)-benzeneacetic acid, methyl ester
Purity: ≥98%
Formula Markup: C19H14O5
Formula Weight: 322,3
Shelf life (days): 1460
CAS Number: 521-52-8
Notes: Vulpinic acid is a lichen metabolite that has been found in L. vulpina and has diverse biological activities.{50292,50293,50294,50295} It is active against C. perfringens, B. vulgatus, B. fragilis, B. loescheii, P. acnes, E. faecium, and methicillin-susceptible and -resistant S. aureus (MICs = 4-16 μg/ml).{50292} Vulpinic acid (25-800 μM) prevents UVB-induced apoptosis, cytotoxicity, and cytoskeletal modifications in HaCaT human keratinocytes.{50293} It also increases scratch wound healing of HaCaT cells.{50294} Vulpinic acid (15 μM) reduces hydrogen peroxide-induced production of reactive oxygen species (ROS) and cytotoxicity in human umbilical vein endothelial cells (HUVECs).{50295}
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