WHI P131, CAS 202475-60-3

JAK3 kinase inhibitor

Product Type: Inhibitor

CAS No.: 202475-60-3

MolecularFormula: C16H15N3O3

Molecular Weight: 297,3

Source: Synthetic

Purity: ≥98%

Solubility: Soluble in DMSO (~1 mg/ml), and DMF (~1 mg/ml)

Appearance: White to off-white solid

PubChem CID: 3794

Scientific Background: WHI P131 also known as Janex-1, is a reversible, potent, and specific inhibitor of JAK3. WHI P131 is cell permeable. It has been seen to inhibit glioblastoma cell adhesion and migration, as well as, thrombin-induced platelet aggregation.

References: 1. Sudbeck E.A., et al. (1999) Clin. Cancer Res: J. Am. Asso. Cancer Res. 5(6): 1569–1582.

Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

• SKU: STRSIH-485-50MG
• Manufacturer: Stressmarq Biosciences
• Manufacturer SKU: SIH-485-50MG
• Green Labware: No
• Package Unit: 50 mg
• Quantity Unit: STK